Senior / Principal Scientist

Highly Competitive
  1. Permanent
  2. Biological Sciences
  3. United States
Boston, USA
Posting date: 02 Apr 2025
64983

Senior / Principal Scientist - Permanent - Boston MA

Proclinical is seeking a dedicated Senior/Principal Scientist specializing in Bioconjugation of antibodies and oligonucleotides.

Primary Responsibilities:

This role will lead the development of antibody-oligonucleotide bioconjugate (AOC) platforms. This position involves collaboration with various teams to advance oligonucleotide conjugates and contribute to an innovative pipeline.

Skills & Requirements:

  • Expertise in biochemistry, protein engineering, or chemical engineering.
  • In-depth knowledge of antibody bioconjugation techniques and linker optimization.
  • Experience with oligonucleotide conjugation.
  • Proficiency in analytical characterization techniques (e.g., SDS-PAGE, SEC, LC-MS/MS).
  • Experience managing contract research organizations (CROs).
  • Strong analytical, research, and organizational skills.

The Senior/Principal Scientist's responsibilities will be:

  • Develop scalable bioconjugation processes for optimizing the AOC platform.
  • Contribute to pipeline development activities by achieving key goals related to antibody mediated oligonucleotide delivery.
  • Establish in-house capabilities for producing and characterizing oligonucleotide bioconjugates.
  • Build cross-functional relationships to ensure smooth transition of AOC methods from research to development.
  • Stay informed on technological advancements in the oligonucleotide/ADC field.
  • Manage timelines and resources for platform activities effectively.

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at m.robinson@proclinical.com

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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