Senior Director, Antibody Bioconjugate Discovery - Boston, MA - Permanent
Proclinical Staffing is seeking a Senior Director, of Antibody Bioconjugate Discovery to join an innovative biotech developing next generation neurogenetic medicines. This is a permanent role located in Boston, MA.
Primary Responsibilities:
In this role, you will oversee all aspects of antibody and antibody bioconjugate technology development and drug discovery to develop next generation CNS therapeutics.
Skills & Requirements:
- PhD in chemistry, biochemistry, chemical biology, or a related field with 10+ years of industry experience
- Demonstrated leadership and management experience with a track record of leading teams and projects to successful endpoints
- Deep expertise in antibody/nanobody generation utilizing a wide range of technologies such as hybridoma, phage display, single B-cell screening, etc.
- Demonstrated experience developing antibody bioconjugates, bispecific and multi-specific antibody formats for receptor-drive tissue targeting
- Familiarity with performing develop ability/manufacturability assessments for selection and optimization of antibodies and antibody formats
- Experience using bioinformatics tools for sequence and structure analysis
- Proven leadership skills with mentoring and leading teams in therapeutic antibody development
- Ability to work collaboratively in a high-paced project team environment, meet deadlines, and prioritize work across multiple projects
- Strong written and verbal communication skills
- Experience in CNS delivery strongly preferred
The Senior Director will:
- Lead efforts in antibody/nanobody development and engineering, including bispecific, single domain, and multi-domain antibodies for non-viral CNS-penetrant therapeutic programs
- Utilize multiple strategies for antibody discovery such as hybridoma screening, B-cell screening, phage display to select and optimize top antibody candidates for affinity, transcytosis and other properties
- Design and execute protein engineering strategies to deliver developable biologics formats by applying molecular biology, structure-guided, computational, combinatorial/display approaches
- Lead and mentor an antibody engineering and molecular biology team of scientists responsible for designing, generating, and characterizing antibody-based therapeutics
- Lead technology development in antibody engineering and contribute to broadening Voyager's intellectual property portfolio
- Hire, manage and develop a team of scientists/research associates fostering an environment of creativity, a strong work ethic and teamwork
- Develop and manage operating budget
If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 857-362-9542 or m.robinson@proclinical.com.
Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.
Proclinical Staffing is an equal opportunity employer.
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