Research Scientist

Research Scientist - Contract - Lexington MA

Proclinical is seeking a Research Scientist specializing in RNAi formulations and biophysics to join a dedicated team.

Primary Responsibilities:

This lab-based role focuses on the formulation and analytical characterization of oligonucleotides for injectable delivery. The successful candidate will work within a diverse team to develop preclinical formulations and translate them into clinical studies.

Skills & Requirements:

• Expertise in pharmaceutical sciences or related disciplines.
• Hands-on experience with synthesis, characterization, and purification techniques such as NMR, HPLC, and Mass Spectrometry.
• Subject matter expertise in nucleic acid therapeutics formulation.
• Ability to establish screening assays for oligonucleotides.
• Experience in analytical method development for complex oligonucleotides.
• Familiarity with high-throughput screening methods like DoE.
• Strong verbal communication and interpersonal skills.
• Awareness of trends and advances in RNA delivery and clinical translation.
• Experience with automation is advantageous.
• Proven publication record in high-quality journals.

The Research Scientist's responsibilities will be:

• Develop preclinical formulations of conjugated oligonucleotides.
• Apply advanced analytical characterization techniques.
• Identify technological gaps and provide research recommendations.
• Manage external collaborations to ensure project deliverables.
• Optimize storage and stability conditions for RNAi conjugates.
• Develop robust analytical methods and assays for quality control.
• Communicate findings through presentations and reports.
• Thrive in a fast-paced, multidisciplinary research environment.

If you are having difficulty in applying or if you have any questions, please contact Jackie Cerchio at j.cerchio@proclinical.com

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.