Senior/Principal Scientist, Protein Science - Permanent - Indianapolis, IN
Proclinical is seeking a Senior/Principal Protein Scientist to join a dynamic discovery group.
Primary Responsibilities:
The successful candidate will be required to focus on the design, production, and characterization of chemical leads and drug candidates. This role is pivotal in advancing a drug discovery portfolio, particularly in the area of metabolic diseases.
Skills & Requirements:
- Advanced degree in Biochemistry, Biology, Chemistry, or related field.
- Expertise in peptide and protein work, purification, and analytical techniques.
- Proficiency with electronic inventory systems and lab notebooks.
- Strong command of Microsoft Suite.
- Self-starter with excellent problem-solving skills.
- Strong organizational and project management abilities.
- Effective communication and interpersonal skills.
- Experience in peptide and protein modification, biophysical techniques, and drug formulation is preferred.
- Knowledge of drug discovery and development processes is advantageous.
The Senior/Principal Scientist's responsibilities will be:
- Design and recommend peptides and proteins with therapeutic potential.
- Conduct or coordinate protein expression and purification.
- Perform chemical conjugation or enzymatic ligation of peptides and proteins.
- Purify drug candidates using techniques like RP-HPLC, IEC, or SEC.
- Formulate drug candidates for downstream screening and analysis.
- Characterize synthesized compounds using LCMS, SEC, and SDS-page.
- Conduct biophysical characterization to ensure compounds meet purity and identity standards.
- Analyze data and present findings to multidisciplinary teams.
- Maintain detailed laboratory records and documentation.
- Collaborate with chemists, biologists, and pharmacologists to advance drug candidates.
- Communicate progress and challenges to stakeholders.
- Ensure compliance with regulatory requirements and safety protocols.
- Participate in laboratory inspections and audits.
Compensation:
- $115,000 to $120,000 per annum.
If you are having difficulty in applying or if you have any questions, please contact Sofia Amark at s.amark@proclinical.com
Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.
Proclinical Staffing is an equal opportunity employer.
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