Scientist/Senior Scientist, Functional Genomics job in South San Francisco, USA

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Last Name*

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First Name*

Last Name*

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Job type: Permanent

Discipline: Senior/Director & VP, Biological Sciences, Pharmacology

Location: United States

This vacancy has now expired. Please see similar roles below...

Proclinical is seeking a Scientist/Senior Scientist, Functional Genomics for a cutting-edge biotechnology company located in South San Francisco, CA.

As a Functional Genomics Scientist/Senior Scientist, you will advance the company's platform for the identification and validation of functional RNA targets for drug discovery.

Must be eligible to work in the US.

Job Responsibilities:

Identify and validate domains in human mRNAs that regulate cellular function including processing, splicing, translation, or stability.
Design, execute, and troubleshoot NGS-based experiments to understand the sequence determinants of RNA regulatory domains.
Recruit, mentor, and oversee research associates.
Analyze, interpret, and organize data, and clearly document and communicate research outcomes to colleagues.
Work within a collaborative, high-caliber, interdisciplinary team.

Skills and Requirements:

Ph.D. in Genetics, Biology, Biochemistry, Bioengineering, or related field.
Deep understanding of mammalian RNA regulation mechanisms.
Experience developing, validating, and applying MPRA or minigene reporter assays for pooled or arrayed screening of RNA function in mammalian cells.
Experience decoding RNA regulation using NGS-based methods, such as RNA-seq, polysome profiling, ribosome footprinting, metabolic labeling, eCLIP, or CRISPR screening.
Proficient in data analysis using Python (or similar language) and common bioinformatics tools.
Mature in scientific thinking and rigorous in recording methodologies and results.
Excellent presentation and writing skills, able to clearly communicate technical information to colleagues.
Ability to plan and execute in a fast-paced environment and agility to adapt to changing priorities.
Excellent presentation and writing skills, ability to clearly communicate technical information to colleagues.
3+ years of relevant industry or post-doctoral research experience.
Familiar with experimental and computational techniques used to measure, model, and analyze RNA structure.
Familiar with concepts and methods in early drug discovery

If you are having difficulty in applying or if you have any questions, please contact Danielle Bahnasy at +(1) 646-868-5142 or d.bahnasy@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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