Research Scientist III LC/MS

Highly Competitive
  1. Contract
  2. Clinical Research Associate (CRA)
  3. United States
Lexington, USA
Posting date: 16 Jul 2024
61384

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Research Scientist III LC/MS -Contract - Lexington MA

Proclinical is seeking a dedicated and innovative LC-MS Analytical Scientist.

Primary Responsibilities:

The successful candidate will focus on developing advanced LC-MS analytical methods for bioanalysis of various molecular formats. This role also involves maintaining lab instruments and supporting the team's knowledge through scientific literature updates and discussions.

Skills & Requirements:

  • PhD or Master's degree in pharmaceutical sciences, analytical chemistry, chemistry, biochemistry or other related disciplines.
  • Superior laboratory skills in biological sample extraction, chromatography, and quantitative/qualitative Mass Spectrometry.
  • Experience with bioanalysis of different molecular formats such as small molecules, peptides, oligonucleotides and/or proteins.
  • Self-motivated with a proactive mindset.
  • Excellent communication skills, both written and oral.
  • Ability to thrive in a multi-disciplinary and fast-paced research environment with tight deadlines.
  • Experience with LC-MS-based ADME and/or bioanalytical assays.
  • Familiarity with Analyst™, Xcalibur™, MassLynx™ and other Mass Spectrometry data-acquisition software packages is preferred.
  • Experience with GraphPad Prism, WinNonlin, Promass, or BioPharma Finder.
  • Knowledge of guidance for industry bioanalytical method validation.

The Research Scientist's responsibilities will be:

  • Develop robust LC-MS analytical methods for bioanalysis of different molecular formats such as small molecules, oligonucleotides, peptides and proteins.
  • Implement high-resolution mass spectrometry-based metabolite profiling and identification platforms.
  • Occasionally perform LC-MS-based small molecule biomarker analysis.
  • Review complex LC-MS-based data sets and articulate findings to project teams.
  • Maintain and troubleshoot lab instruments such as biological sample extraction systems, HPLC, and LC-MS.
  • Contribute to the team's knowledge through updating scientific literature and discussions.

If you are having difficulty in applying or if you have any questions, please contact Mike Raletz at m.raletz@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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